Clarisse Machanguana (born 4 October 1976) is a professional women’s basketball player from Mozambique. She has played internationally in both the United States (WNBA from 1999–2002) and in Spain (FC Barcelona since 2003). She also represented Mozambique at the 2006 Lusophony Games in Macau, China.

Now she has her own foundation with a vision for youth, sports, and to combat sexually tranmitted diseases.